Establishment and investigation of a surgical model of hypothyroidism in Wistar rats

Surgical removal of the thyroid gland can be used to successfully establish a hypothyroid rat model that is stable and reliable and can provide a model basis for hypothyroidism-related research.

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Publication Details

Journal
PLoS ONE
Published
2026-01-20
DOI
https://doi.org/10.1371/journal.pone.0340302
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Establishment and investigation of a surgical model of hypothyroidism in Wistar rats

Luming Zheng, Qingqing He, Chao Yu, Chunyu Chu et al.
PLoS ONE
Thyroid Disorders and Treatments
article

Establishment and investigation of a surgical model of hypothyroidism in Wistar rats

Luming Zheng, Qingqing He, Chao Yu, Chunyu Chu, Zhonghui Li, Yuan Liu, Xiao LIU, Fang Yu, Meng Wang, Yue Wang, Han Gao, Yuanyuan Fu, Jiayu Zhu
article en

Abstract

Surgical removal of the thyroid gland can be used to successfully establish a hypothyroid rat model that is stable and reliable and can provide a model basis for hypothyroidism-related research.

PLoS ONEVol. 21(1)
Weifang Medical University (CN), Shandong University of Traditional Chinese Medicine (CN), People's Liberation Army 401 Hospital (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 84%
Thyroid Disorders and Treatments
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Establishment and investigation of a surgical model of hypothyroidism in Wistar rats — Luming Zheng, Qingqing He, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS