The impact of a potassium-enriched salt substitute on blood pressure control in patients with resistant arterial hypertension: A randomized pilot trial
In this randomized pilot trial, the use of a potassium-enriched salt substitute was safe and associated with modest, directionally greater reductions in ambulatory BP compared with regular salt in patients with RAH. These findings support the feasibility and safety of potassium-enriched salt substitution as a pragmatic adjunctive strategy for blood pressure management in patients with resistant hypertension.
Authors
- Yasmin de Souza Lima Bitar (ORCID: https://orcid.org/0000-0003-0125-2261)
- Ana Beatriz Cazé Cerón
- André Rodrigues Durães (ORCID: https://orcid.org/0000-0002-1506-0327)
- Tomaz Mattedi Carvalho
- Gabriele Eliza Assis (ORCID: https://orcid.org/0009-0007-2953-5323)
- Marina Pereira Ferreira
- Jorge Luís Motta dos Anjos
- Cristiano Ricardo Bastos de Macedo
- Jackson Pedro Barros Pereira
- Apoenna Marina Noronha Brito
- Enilson Carmo Barbosa dos Santos
- Victoria Bastos Rodrigues
Institutions
- Universidade Federal da Bahia (BR)
- Universidade do Estado da Bahia (BR)
- Complexo Hospitalar Universitário Professor Edgard Santos (BR)
- Universidade Federal de Uberlândia (BR)
Publication Details
- Journal
- Contemporary Clinical Trials
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1016/j.cct.2026.108230
- Primary Topic
- Sodium Intake and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00