The effect of Apolipoprotein E4 on cognitive function in Parkinson’s disease: A structural MRI study in the PPMI cohort
This study suggests that APOE4 may not influence cognitive function in PD by affecting GMV and CTh. However, longitudinal analyses must confirm these observations.
Authors
- Angenelle Eve Rosal
- Isabelle Boileau
- Edgardo Torres-Carmona
- Ariel Graff-Guerrero
- Sarah L. Martin
- Antonio P. Strafella
Institutions
- University Health Network (CA)
- Centre for Addiction and Mental Health (CA)
- University of Toronto (CA)
- Toronto Western Hospital (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1371/journal.pone.0341240
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00