Efficacy and Safety of HAIC Combined with PD-(L)1 Inhibitors and Bevacizumab Versus HAIC with PD-(L)1 Inhibitors and TKIs in Advanced Hepatocellular Carcinoma: A Retrospective Cohort Study

Bevacizumab-containing triplet therapy was associated with improved tumor control and delayed progression compared to TKIs-based regimens in advanced HCC. The higher bleeding risk in the bevacizumab group highlights the necessity of standardized baseline evaluation and adequate preventive measures.

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Journal
Cancers
Published
2026-01-20
DOI
https://doi.org/10.3390/cancers18020314
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Efficacy and Safety of HAIC Combined with PD-(L)1 Inhibitors and Bevacizumab Versus HAIC with PD-(L)1 Inhibitors and TKIs in Advanced Hepatocellular Carcinoma: A Retrospective Cohort Study

Songlin Song, Z. F. Wang, Yiming Liu, Jianwen Liu et al.
Cancers
Hepatocellular Carcinoma Treatment and Prognosis
article

Efficacy and Safety of HAIC Combined with PD-(L)1 Inhibitors and Bevacizumab Versus HAIC with PD-(L)1 Inhibitors and TKIs in Advanced Hepatocellular Carcinoma: A Retrospective Cohort Study

Songlin Song, Z. F. Wang, Yiming Liu, Jianwen Liu, Wei Xu, B. Liang, Chuansheng Zheng, Xuefeng Kan, Yanqiao Ren
article en

Abstract

Bevacizumab-containing triplet therapy was associated with improved tumor control and delayed progression compared to TKIs-based regimens in advanced HCC. The higher bleeding risk in the bevacizumab group highlights the necessity of standardized baseline evaluation and adequate preventive measures.

CancersVol. 18(2)
Precision for Medicine (United States) (US), Union Hospital (CN), Hubei University (CN)
Good health and well-being
Openalex Percentile: Top 82%
Hepatocellular Carcinoma Treatment and Prognosis
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