Sex differences in electrocardiograms of trained athletes: a systematic review and meta-analysis

Compared to male athletes, female athletes were twice as likely to have abnormal TWI and six times as likely to have isolated TWIV1-V3, a finding which was not accompanied by diagnoses of cardiac pathology in female athletes. These data should help inform sex-specific aspects of athlete ECG screening guidelines.

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Publication Details

Journal
European Journal of Preventive Cardiology
Published
2026-01-03
DOI
https://doi.org/10.1093/eurjpc/zwag004
Primary Topic
Cardiovascular Effects of Exercise
Type
article
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article

Sex differences in electrocardiograms of trained athletes: a systematic review and meta-analysis

Ludmila Cosío-Lima, Simone Ungaro, Bradley J. Petek, Tochukwu F. Ilodibia et al.
European Journal of Preventive Cardiology
Cardiovascular Effects of Exercise
article

Sex differences in electrocardiograms of trained athletes: a systematic review and meta-analysis

Ludmila Cosío-Lima, Simone Ungaro, Bradley J. Petek, Tochukwu F. Ilodibia, Angus Davis, Sameera Mukhtar, Tim Driscoll, Alessandro Zorzi, Hamish MacLachlan, Belinda Gray, Wojciech Krol, Rheannon van der Linden, Jessica J Orchard, Danica Sardelich
article en

Abstract

Compared to male athletes, female athletes were twice as likely to have abnormal TWI and six times as likely to have isolated TWIV1-V3, a finding which was not accompanied by diagnoses of cardiac pathology in female athletes. These data should help inform sex-specific aspects of athlete ECG screening guidelines.

European Journal of Preventive Cardiology
United States Army Medical Command (US), The University of Sydney (AU), University of Padua (IT), Oregon Health & Science University (US), St George's, University of London (GB), Medical University of Warsaw (PL), Royal Prince Alfred Hospital (AU), United States Army Combat Capabilities Development Command (US), Cooperative Trials Group for Neuro-Oncology (AU), The George Institute for Global Health (AU), University of West Florida (US)
Gender equality
Openalex Percentile: Top 84%
Cardiovascular Effects of Exercise
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Sex differences in electrocardiograms of trained athletes: a systematic review and meta-analysis — Ludmila Cosío-Lima, Simone Ungaro, et al. · European Journal of Preventive Cardiology (2026) | TGRS Research Map | TGRS