Identification of endogenous reference genes for RT-qPCR analysis in breast cancer and matched adjacent tissues

TFRC and 18S rRNA may be suitable RGs in breast cancer tissues, while all five candidates were not stable in adjacent tissues. Larger studies are needed to confirm these findings.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-20
DOI
https://doi.org/10.3389/fonc.2025.1702210
Primary Topic
Molecular Biology Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of endogenous reference genes for RT-qPCR analysis in breast cancer and matched adjacent tissues

Zhong-Qi Qiao, Yan Xu, Yan-Duo Chen, K Zhang et al.
Frontiers in Oncology
Molecular Biology Techniques and Applications
article

Identification of endogenous reference genes for RT-qPCR analysis in breast cancer and matched adjacent tissues

Zhong-Qi Qiao, Yan Xu, Yan-Duo Chen, K Zhang, Zhi-bao Xu, Can Liu, Ya-Wen Wang, Yue Meng
article en

Abstract

TFRC and 18S rRNA may be suitable RGs in breast cancer tissues, while all five candidates were not stable in adjacent tissues. Larger studies are needed to confirm these findings.

Frontiers in OncologyVol. 15
Taizhou Second People's Hospital (CN), Fourth People’s Hospital of Jinan (CN), Jinan Central Hospital (CN), Binzhou People's Hospital (CN), National Clinical Research (US), National Center for Infectious Diseases (US), Qilu Hospital of Shandong University (CN), Shandong First Medical University (CN), State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University (CN)
Natural Science Foundation of Shandong Province
Good health and well-being
Openalex Percentile: Top 84%
Molecular Biology Techniques and Applications
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Identification of endogenous reference genes for RT-qPCR analysis in breast cancer and matched adjacent tissues — Zhong-Qi Qiao, Yan Xu, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS