An unexpected finding of large bowel obstruction from colonic diaphragm disease following prolonged use of indomethacin
Colonic stricture leading to large bowel obstruction is an uncommon presentation to the emergency department. Strictures are commonly established secondary to diverticular disease, inflammatory bowel disease, malignancy or ischaemic/infective colitis. The formation of a colonic stricture secondary to the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) is an unusual finding. We present a case of a 48-year-old lady who presented with a large bowel obstruction secondary to NSAID-induced right colonic stricture in a patient who was initially thought to have an index presentation of colonic Crohn's disease.
Authors
- Evangeline Woodford (ORCID: https://orcid.org/0000-0001-6622-788X)
- Raymond Kwok (ORCID: https://orcid.org/0000-0003-4506-9303)
- Isabella Zappala (ORCID: https://orcid.org/0009-0006-9188-827X)
- Joseph Do Woong Choi
- Peter Dutton
Institutions
- The University of Sydney (AU)
- Norwood Hospital (US)
- Westmead Hospital (AU)
- Cooperative Trials Group for Neuro-Oncology (AU)
Publication Details
- Journal
- Journal of Surgical Case Reports
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1093/jscr/rjaf1074
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00