Targeting endometrial stem cell in endometriosis treatment, a scoping review

EnSCs sustain aberrant cellular behaviours in endometriosis. Targeting EnSCs and their related pathways may be an innovative, individualized, and disease-modifying strategy. Pharmacological modulation, gene therapy and exosome are strategies for stem cell inhibition in endometriosis, being a promising avenue for future research leading to application in clinical practice.

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Publication Details

Journal
Journal of Gynecology Obstetrics and Human Reproduction
Published
2026-01-20
DOI
https://doi.org/10.1016/j.jogoh.2026.103123
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Targeting endometrial stem cell in endometriosis treatment, a scoping review

Vanessa Vieira, Bárbara Laranjeiro, Fernanda Santos, Carlota Anjinho-Carvalhos et al.
Journal of Gynecology Obstetrics and Human Reproduction
Endometriosis Research and Treatment
article

Targeting endometrial stem cell in endometriosis treatment, a scoping review

Vanessa Vieira, Bárbara Laranjeiro, Fernanda Santos, Carlota Anjinho-Carvalhos, Maria João Carvalho, Mariana Robalo-Cordeiro, Margarida Figueiredo-Dias, Ana Aparício
article en

Abstract

EnSCs sustain aberrant cellular behaviours in endometriosis. Targeting EnSCs and their related pathways may be an innovative, individualized, and disease-modifying strategy. Pharmacological modulation, gene therapy and exosome are strategies for stem cell inhibition in endometriosis, being a promising avenue for future research leading to application in clinical practice.

Journal of Gynecology Obstetrics and Human ReproductionVol. 55(4)
Escola Superior de Tecnologia da Saúde de Coimbra (PT), University of Coimbra (PT)
Openalex Percentile: Top 84%
Endometriosis Research and Treatment
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