The development of orthodontic elastomeric ligature with sustained fluoride-releasing for the prevention of white spot lesions: an in vitro feasibility study
Our study demonstrated Ca-F O-rings displayed sustained fluoride release under <i>in vitro</i> conditions, indicating potential clinical relevance for reducing WSLs during orthodontic treatment. This work represents an early-stage feasibility study and warrants further validation with larger-scale and <i>in vivo</i> conditions.
Authors
- Reginald W. Taylor (ORCID: https://orcid.org/0000-0003-0013-4343)
- Peter H. Buschang (ORCID: https://orcid.org/0000-0003-4397-6815)
- Amal Noureldin (ORCID: https://orcid.org/0000-0002-3857-3125)
- Matthew J. Kesterke (ORCID: https://orcid.org/0000-0002-6798-6682)
- Kativa Strickland
- Yan Jing
- Chi Ma
- Ying Liu
Institutions
- American Association of Orthodontists (US)
- Scottish Rite Freemasonry (US)
- Texas A&M Health Science Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fbioe.2025.1671922
- Primary Topic
- Dental materials and restorations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- National Institute of Dental and Craniofacial Research