Elucidate senescence-related gene signature and immune infiltration landscape in abdominal aortic aneurysm

This study identified senescence-related biomarkers associated with AAA through transcriptomic public databases, revealing their potential functional mechanisms, relationships with immune cells, and associations with AAA subtypes. These results could offer novel candidate targets for both diagnostic and therapeutic strategies in AAA.

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Publication Details

Journal
PLoS ONE
Published
2026-01-20
DOI
https://doi.org/10.1371/journal.pone.0340976
Primary Topic
Aortic aneurysm repair treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Elucidate senescence-related gene signature and immune infiltration landscape in abdominal aortic aneurysm

Ru Ying, Jingde Li, Xin Guo, Jing Luo et al.
PLoS ONE
Aortic aneurysm repair treatments
article

Elucidate senescence-related gene signature and immune infiltration landscape in abdominal aortic aneurysm

Ru Ying, Jingde Li, Xin Guo, Jing Luo, Min Zhang
article en

Abstract

This study identified senescence-related biomarkers associated with AAA through transcriptomic public databases, revealing their potential functional mechanisms, relationships with immune cells, and associations with AAA subtypes. These results could offer novel candidate targets for both diagnostic and therapeutic strategies in AAA.

PLoS ONEVol. 21(1)
Nanchang University (CN), Central Hospital of Wuhan (CN), First Affiliated Hospital of Nanchang University (CN), Huazhong University of Science and Technology (CN)
National Natural Science Foundation of China
Reduced inequalities
Openalex Percentile: Top 85%
Aortic aneurysm repair treatments
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