Arterio-venous gradient of active interleukin-18 is associated with diastolic dysfunction: a cross-sectional study
The aIL-18 A/V ratio correlated with markers of diastolic dysfunction, particularly in patients with increased filling pressure. These exploratory findings indicate an association between local IL-18 gradients and diastolic dysfunction, warranting further investigation.
Authors
- Takeshi Urano (ORCID: https://orcid.org/0000-0003-3383-3554)
- Kazuaki Tanabe (ORCID: https://orcid.org/0000-0002-8910-8389)
- Keizo Kanasaki (ORCID: https://orcid.org/0000-0002-9563-502X)
- Hiroki Kamino (ORCID: https://orcid.org/0000-0002-2489-0453)
- Yusuke Morita (ORCID: https://orcid.org/0000-0002-4419-3874)
- Akihiro Endo
- Yuzo Kagawa
- Yu Yasuda
- Hirofumi Makino
- Hiroshi Kawahara
Institutions
- Shimane University (JP)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1093/eschf/xvaf041
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00