Hemorrhagic transformation following a malignant middle cerebral artery infarction

HT is highly prevalent in malignant MCA infarction, regardless of IVT administration, with the majority of cases asymptomatic. Consequently, these findings suggest that asymptomatic HT may represent a natural progression of large infarcts rather than a treatment complication. The results underscore the need for early diagnostic markers and improved management strategies for HT in malignant MCA infarction.

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Publication Details

Journal
Journal of Cerebrovascular and Endovascular Neurosurgery
Published
2026-01-20
DOI
https://doi.org/10.7461/jcen.2026.e2025.05.001
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Hemorrhagic transformation following a malignant middle cerebral artery infarction

Manvi Khandelwal, З. А. Гончарова, Salah Sehweil, Prashanth Nataraj
Journal of Cerebrovascular and Endovascular Neurosurgery
Intracerebral and Subarachnoid Hemorrhage Research
article

Hemorrhagic transformation following a malignant middle cerebral artery infarction

Manvi Khandelwal, З. А. Гончарова, Salah Sehweil, Prashanth Nataraj
article en

Abstract

HT is highly prevalent in malignant MCA infarction, regardless of IVT administration, with the majority of cases asymptomatic. Consequently, these findings suggest that asymptomatic HT may represent a natural progression of large infarcts rather than a treatment complication. The results underscore the need for early diagnostic markers and improved management strategies for HT in malignant MCA infarction.

Journal of Cerebrovascular and Endovascular Neurosurgery
Rostov State Medical University (RU)
Good health and well-being
Openalex Percentile: Top 84%
Intracerebral and Subarachnoid Hemorrhage Research
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