Mutational profiling of HIV+ diffuse large B-cell lymphoma reveals distinct mutational features with evidence of genomic instability
Together, these results highlight distinct tumorigenic mechanisms in HIV+ DLBCL and underscore the need for mutational profiling of HIV+ DLBCL cohorts worldwide to identify biomarkers and therapeutic targets.
Authors
- Melinda S. Yates (ORCID: https://orcid.org/0000-0001-9450-5517)
- Samantha Beck (ORCID: https://orcid.org/0000-0002-2718-2786)
- Alexander M. Xu (ORCID: https://orcid.org/0000-0003-4877-4358)
- Steven Vensko (ORCID: https://orcid.org/0000-0001-9399-5999)
- Jenny Coelho (ORCID: https://orcid.org/0009-0002-9155-4174)
- Sophia Maharry Roush (ORCID: https://orcid.org/0000-0001-8686-1570)
- Amon Chirwa (ORCID: https://orcid.org/0009-0003-9301-9674)
- Jonathan Galeotti
- Akil Merchant
- Maurice Mulenga
- Russell Broaddus
- Satish Gopal
- Edwards Kasonkanji
- Marriam Mponda
- Matthew S. Painschab
Institutions
- University of North Carolina at Chapel Hill (US)
- Cedars-Sinai Medical Center (US)
- University of North Carolina Health Care (US)
- Kamuzu Central Hospital (MW)
- Center for Global Health (US)
- National Cancer Institute (US)
- UNC Lineberger Comprehensive Cancer Center
- Kamuzu University of Health Sciences (MW)
- University of Maryland, College Park (US)
Publication Details
- Journal
- AIDS
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1097/qad.0000000000004443
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Cancer Institute
- Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill