Association between iron deficiency anemia and the risk of new-onset tuberculosis infection: a matched cohort analysis

IDA demonstrated a significant association with increased tuberculosis risk in this multinational cohort, particularly during early follow-up and for extrapulmonary manifestations. These findings suggest that IDA may represent an underrecognized modifiable risk factor for tuberculosis. Future research is warranted to validate these findings, with particular attention to the potential modifying effect of iron supplementation on tuberculosis risk.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-01-20
DOI
https://doi.org/10.3389/fnut.2026.1727992
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between iron deficiency anemia and the risk of new-onset tuberculosis infection: a matched cohort analysis

Ying-Jen Chang, Li-Chen Chang, Yi-Chen Lai, Kuo-Chuan Hung et al.
Frontiers in Nutrition
Iron Metabolism and Disorders
article

Association between iron deficiency anemia and the risk of new-onset tuberculosis infection: a matched cohort analysis

Ying-Jen Chang, Li-Chen Chang, Yi-Chen Lai, Kuo-Chuan Hung, I-Wen Chen
article en

Abstract

IDA demonstrated a significant association with increased tuberculosis risk in this multinational cohort, particularly during early follow-up and for extrapulmonary manifestations. These findings suggest that IDA may represent an underrecognized modifiable risk factor for tuberculosis. Future research is warranted to validate these findings, with particular attention to the potential modifying effect of iron supplementation on tuberculosis risk.

Frontiers in NutritionVol. 13
E-Da Hospital (TW), Chi Mei Medical Center (TW), I-Shou University (TW)
Zero hunger
Openalex Percentile: Top 85%
Iron Metabolism and Disorders
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