Single-cell RNA sequencing revealed cell heterogeneity in sagittal suture mesenchyme
This study provides the first identification of TACs within the developing cranial suture niche and elucidates key regulatory genes and signaling networks in SuSCs and TACs, thereby providing a theoretical framework for understanding the mechanisms underlying cranial suture formation and homeostasis.
Authors
- Weihui Chen (ORCID: https://orcid.org/0000-0003-2571-7959)
- Jie Chen (ORCID: https://orcid.org/0000-0002-9254-4413)
- Ran Wu
- Chengyan Ren
- K. Sun
- Hu Zhao
- Chenxin Geng
Institutions
- Wuhan University (CN)
- Chinese Institute for Brain Research (CN)
- National Clinical Research (US)
- Stomatology Hospital (CN)
- Union Hospital (US)
- Huashan Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fcell.2026.1725375
- Primary Topic
- Craniofacial Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China