Development of a colorimetric RT-LAMP-based microfluidic device for SARS-CoV-2 detection

The colorimetric RT-LAMP-based microfluidic device enables simple, rapid, and reliable detection of SARS-CoV-2 RNA with high specificity and sensitivity. The device enables visual detection of results and requires only simple equipment, making it suitable as a practical molecular detection tool for point-of-care and resource-limited settings. In terms of detection performance, our findings, when considered alongside previously published data, indicate that the sensitivity and specificity of the device are comparable to or exceed those of lateral flow tests commonly used for point-of-care COVID-19 diagnostics.