Predictors of pneumonitis in patients treated with systemic therapy and radiotherapy for localized triple negative or HER2 positive breast cancer

Overall, the probability of G2P+ in patients receiving radiotherapy for HER2+ or TN BC is low. However, concurrent T-DM1 and radiotherapy was associated with significantly higher rates of pneumonitis than previously reported, suggesting a cautionary approach when combining the two therapies.

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Publication Details

Journal
The Breast
Published
2026-01-20
DOI
https://doi.org/10.1016/j.breast.2026.104706
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Predictors of pneumonitis in patients treated with systemic therapy and radiotherapy for localized triple negative or HER2 positive breast cancer

X. Ye, E. Amir, Ezra Hahn, A. Hope et al.
The Breast
Breast Cancer Treatment Studies
article

Predictors of pneumonitis in patients treated with systemic therapy and radiotherapy for localized triple negative or HER2 positive breast cancer

X. Ye, E. Amir, Ezra Hahn, A. Hope, Tony Tadic, Z. Liu, C.Anne Koch, Hannah Bacon, Grace Lee
article en

Abstract

Overall, the probability of G2P+ in patients receiving radiotherapy for HER2+ or TN BC is low. However, concurrent T-DM1 and radiotherapy was associated with significantly higher rates of pneumonitis than previously reported, suggesting a cautionary approach when combining the two therapies.

The BreastVol. 86
University Health Network (CA), University of Toronto (CA), Princess Margaret Cancer Centre (CA)
Good health and well-being
Openalex Percentile: Top 84%
Breast Cancer Treatment Studies
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