Polygenic risk and air pollution trends in relation to type 2 diabetes: evidence from the Taiwan Biobank
Both worsening PM<sub>2.5</sub> exposure and PRS were associated with T2D. The observed PM<sub>2.5</sub> and PRS interaction was weak and should be interpreted cautiously. Our findings highlight the importance of improving air quality and adopting personalized prevention strategies for individuals with high genetic risk.
Authors
- Ai‐Ru Hsieh
- Bing-Fang Hwang Hwang
- Chau‐Ren Jung (ORCID: https://orcid.org/0000-0003-0673-9968)
- Osama Aziz
Institutions
- China Medical University (TW)
- National Institute for Environmental Studies (JP)
- National Taipei University (TW)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1186/s13098-026-02088-1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00