Revisiting the INSPIRE trial: antibody profiling reveals high prevalence of occult autoimmunity
IP analyses demonstrated an unexpectedly high prevalence of autoantibodies potentially indicative of underlying connective tissue disease-associated ILD, underscoring the importance of classification schemes incorporating unbiased autoantibody profiling.
Authors
- Dana P. Ascherman (ORCID: https://orcid.org/0000-0002-1387-0860)
- Cindy Burg
- Simone Pereira-Simon
- Benjamin Trzaskoma
- Noreen Fertig
- Jonathan S. Minden (ORCID: https://orcid.org/0000-0003-3175-393X)
- Hannah VanEvery (ORCID: https://orcid.org/0000-0002-0778-0607)
- Sharon J. Elliot (ORCID: https://orcid.org/0000-0001-8622-1389)
- Stephanie Biedka (ORCID: https://orcid.org/0000-0001-8167-037X)
- Marilyn K. Glassberg (ORCID: https://orcid.org/0000-0003-1990-6614)
- Yingze Zhang (ORCID: https://orcid.org/0000-0001-8042-6105)
- Lisa L. Harlow (ORCID: https://orcid.org/0000-0001-8001-4178)
Institutions
- Loyola University Medical Center (US)
- University of Miami (US)
- University of Pittsburgh (US)
- Loyola University Chicago (US)
- Immediate Post Concussion Assessment and Cognitive Testing (United States) (US)
- Impact Technology Development (United States) (US)
- La Roche College (US)
Publication Details
- Journal
- Respiratory Research
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1186/s12931-025-03490-5
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00