Korean Red Ginseng attenuates glucocorticoid-induced skin barrier dysfunction via mineralocorticoid receptor modulation
This study elucidates the pivotal role of MR in mediating GC-induced skin barrier dysfunction and identifies Rg3(R) from KRG as a promising therapeutic candidate for restoring skin barrier integrity. The findings provide a mechanistic basis for targeting MR signaling in the development of novel interventions for GC-associated skin disorders.
Authors
- No-June Park (ORCID: https://orcid.org/0000-0001-5528-6446)
- Prasannavenkatesh Durai (ORCID: https://orcid.org/0000-0002-1538-8349)
- Jin Woo Lee
- Keunwan Park
- Yong Kee Kim
- Yujung Jung
- Su-Nam Kim
Institutions
- Sookmyung Women's University (KR)
- Korea Institute of Science and Technology (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1016/j.jgr.2026.100980
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00