Risk of acute pancreatitis with <scp>DPP</scp> ‐4 inhibitors versus <scp>SGLT2</scp> inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

Although small differences cannot be excluded given the width of the CIs for the estimated HRs, the small IRDs observed suggest that any potential difference, if present, is likely to be clinically modest. Therefore, acute pancreatitis risk may not be a major determinant when selecting initial therapy.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-20
DOI
https://doi.org/10.1111/dom.70490
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Risk of acute pancreatitis with DPP ‐4 inhibitors versus SGLT2 inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

Y Kimura, Hideo Yasunaga, Akira Okada, Takashi Tatewaki
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
article

Risk of acute pancreatitis with DPP ‐4 inhibitors versus SGLT2 inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

Y Kimura, Hideo Yasunaga, Akira Okada, Takashi Tatewaki
article en

Abstract

Although small differences cannot be excluded given the width of the CIs for the estimated HRs, the small IRDs observed suggest that any potential difference, if present, is likely to be clinically modest. Therefore, acute pancreatitis risk may not be a major determinant when selecting initial therapy.

Diabetes Obesity and MetabolismVol. 28(4)
University of Tokyo Health Sciences (JP), The University of Tokyo (JP)
Japan Association for Diabetes Education and Care, Ministry of Health, Labour and Welfare, University of Tokyo
Good health and well-being
Openalex Percentile: Top 84%
Diabetes Treatment and Management
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