Gene expression profiling identifies ferroptosis-related genes and pathways in human colon cancers cell lines
Our findings highlight <i>ASNS, CHAC1, PCK2, DDIT4, and ATF3/4</i> as potential biomarkers for ferroptosis in CRC. Monitoring the expression of these genes may help identify patients who are responsive to ferroptosis inducers and facilitate the development of personalized treatment strategies.
Authors
- Tokar Erik J.
- Carri Murphy
- Birandra K. Sinha
- Ruchir Shah
- M. Balik-Meisner
- K. R. Shockley
- D. Mav
- D. Phadke
Institutions
- National Institutes of Health (US)
- Scion (NZ)
- National Institute of Environmental Health Sciences (US)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fmolb.2025.1680206
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Environmental Health Sciences