Management of airway hemorrhage with endobronchial valve in patients undergoing pulmonary endarterectomy- an expert center experience: a case report

Pulmonary endarterectomy is an established treatment for selected patients with chronic thromboembolic pulmonary hypertension. And bleeding into the airways is a feared complication of this surgical technique. Although its incidence is relatively low (0.4–6%), its mortality rate remains very high (> 50%). Its current management involves isolating the source of bleeding with a bronchial blocker or, if necessary, using a double-lumen endotracheal tube. In our case, we describe the use of endobronchial valve instead of blocker to treat source of bleeding. The procedure we chose has not yet been described in the literature. A 55-year-old man with chronic thromboembolic pulmonary hypertension underwent PEA during a 41-minute deep hypothermic cardiac arrest. During normothermia, prior to disconnection from the cardiopulmonary bypass, blood was detected in the endotracheal tube. Approximately 800 ml of fresh blood was aspirated from the endotracheal tube. The patient was connected to central veno-arterial extracorporeal membrane oxygenation (V-A ECMO), and his coagulation was normalised. The summoned pneumologist detected the source of bleeding in the right B2 segment, where one endobronchial valve was implanted. No further bleeding occurred, the V-A ECMO was disconnected after 122 minutes, the surgery was concluded, and the patient was transferred to the postoperative intensive care unit. Heparinization was initiated soon after surgery. The patient was extubated on the first postoperative day. The valve was removed on the 7th postoperative day by the pneumologist under topical anaesthesia with sedation in a short heparin-free window. Compared to bronchial blocker, EBV can offer several advantages including reduction in days on mechanical ventilation, reduced risk of device dislodgment and earlier initiation of postoperative anticoagulant therapy. If confirmed by randomised studies, this technique could contribute to improving morbidity and mortality in this feared complication.

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Journal
BMC Anesthesiology
Published
2026-01-20
DOI
https://doi.org/10.1186/s12871-026-03610-8
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Management of airway hemorrhage with endobronchial valve in patients undergoing pulmonary endarterectomy- an expert center experience: a case report

Tomáš Brožek, Jaroslav Lindner, Jan Kunstýř, Tomáš Prskavec et al.
BMC Anesthesiology
Pulmonary Hypertension Research and Treatments
article

Management of airway hemorrhage with endobronchial valve in patients undergoing pulmonary endarterectomy- an expert center experience: a case report

Tomáš Brožek, Jaroslav Lindner, Jan Kunstýř, Tomáš Prskavec, Michal Lipš, Matúš Nižňanský, Jiří Votruba, Pavel Michálek
article en

Abstract

Pulmonary endarterectomy is an established treatment for selected patients with chronic thromboembolic pulmonary hypertension. And bleeding into the airways is a feared complication of this surgical technique. Although its incidence is relatively low (0.4–6%), its mortality rate remains very high (> 50%). Its current management involves isolating the source of bleeding with a bronchial blocker or, if necessary, using a double-lumen endotracheal tube. In our case, we describe the use of endobronchial valve instead of blocker to treat source of bleeding. The procedure we chose has not yet been described in the literature. A 55-year-old man with chronic thromboembolic pulmonary hypertension underwent PEA during a 41-minute deep hypothermic cardiac arrest. During normothermia, prior to disconnection from the cardiopulmonary bypass, blood was detected in the endotracheal tube. Approximately 800 ml of fresh blood was aspirated from the endotracheal tube. The patient was connected to central veno-arterial extracorporeal membrane oxygenation (V-A ECMO), and his coagulation was normalised. The summoned pneumologist detected the source of bleeding in the right B2 segment, where one endobronchial valve was implanted. No further bleeding occurred, the V-A ECMO was disconnected after 122 minutes, the surgery was concluded, and the patient was transferred to the postoperative intensive care unit. Heparinization was initiated soon after surgery. The patient was extubated on the first postoperative day. The valve was removed on the 7th postoperative day by the pneumologist under topical anaesthesia with sedation in a short heparin-free window. Compared to bronchial blocker, EBV can offer several advantages including reduction in days on mechanical ventilation, reduced risk of device dislodgment and earlier initiation of postoperative anticoagulant therapy. If confirmed by randomised studies, this technique could contribute to improving morbidity and mortality in this feared complication.

BMC AnesthesiologyVol. 26(1)
Charles University (CZ), General University Hospital in Prague (CZ)
Good health and well-being
Openalex Percentile: Top 85%
Pulmonary Hypertension Research and Treatments
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