Evidence-based indications for proton therapy in adults determined using the GRADE approach
PT shows variable, cancer-specific results and does not consistently outperform XRT. Some indications appear promising, but substantial evidence gaps persist, emphasizing the need for high-quality comparative studies and systematic clinical data collection.
Authors
- Carles Gomà (ORCID: https://orcid.org/0000-0003-0336-390X)
- Carolina Moltó-Puigmartí (ORCID: https://orcid.org/0000-0001-6831-6210)
- Lucía Alonso García
- Clara Pons Duran
- Sara Pedraza Fernández
- Jordi L. Giralt
- Maria-Dolors Estrada Sabadell
- Rosa Maria Vivanco Hidalgo
Institutions
- Universitat Autònoma de Barcelona (ES)
- Hospital Universitario 12 De Octubre (ES)
- Vall d'Hebron Institut de Recerca (ES)
- Hospital Clínic de Barcelona (ES)
- Agència de Qualitat i Avaluació Sanitàries de Catalunya (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
Publication Details
- Journal
- Clinical & Translational Oncology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1007/s12094-025-04083-w
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- McMaster University