Environmental Stressors and Cardiovascular Health: Acting Locally for Global Impact in a Changing World

Non-communicable diseases (NCDs) account for 70% of global mortality and are responsible for over 38 million deaths annually, with cardiovascular disease (CVD) constituting most of these fatalities. While traditional risk factors for CVD have long been recognized, there is growing evidence that a rising prevalence of ubiquitous environmental risk factors (ERFs) may play an increasingly significant role in the genesis and rising prevalence of NCDs. ERFs include many interconnected anthropogenic exposures with cumulative compound health impacts, including air pollution, noise exposure, artificial light at night, plastic pollution, chemical pollution and the various effects of climate change, such as heat extremes, desert storms, floods and wildfires. Urbanization has intensified the impact of many ERFs and created intense exposure environments, highlighting the urgency and the opportunity to address these for maximum public health benefit. Impactful intervention often requires regulatory and policy-driven efforts addressing the genesis of exposures and minimizes their health impact, particularly in vulnerable populations who may contribute the least but may be impacted the most. Solutions must involve the development of resiliency and adaptation measures to a changing world, where the probability of sudden catastrophic and cascading events is much more likely. Political will and international cooperation are essential in establishing and enforcing regulations that promote cleaner air and water, quieter and natural biodiverse environments, and sustainable infrastructure in urban, and rural medical facilities. Integration of planetary and environmental health into cardiovascular care will be vital in reducing the burden of NCDs globally. By addressing the root causes of environmental stressors, it is possible to reduce the incidence of CVDs and promote healthier, just and sustainable societies.

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Publication Details

Journal
Journal of the American College of Cardiology
Published
2026-01-20
DOI
https://doi.org/10.1016/j.jacc.2026.01.015
Primary Topic
Climate Change and Health Impacts
Type
article
Field-Weighted Citation Impact
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article

Environmental Stressors and Cardiovascular Health: Acting Locally for Global Impact in a Changing World

Amam Mbakwem, Thomas Münzel, Keith Churchwell, Thomas Lüscher et al.
Journal of the American College of Cardiology
Climate Change and Health Impacts
article

Environmental Stressors and Cardiovascular Health: Acting Locally for Global Impact in a Changing World

Amam Mbakwem, Thomas Münzel, Keith Churchwell, Thomas Lüscher, Christopher M. Kramer, Sanjay Rajagopalan
article en

Abstract

Non-communicable diseases (NCDs) account for 70% of global mortality and are responsible for over 38 million deaths annually, with cardiovascular disease (CVD) constituting most of these fatalities. While traditional risk factors for CVD have long been recognized, there is growing evidence that a rising prevalence of ubiquitous environmental risk factors (ERFs) may play an increasingly significant role in the genesis and rising prevalence of NCDs. ERFs include many interconnected anthropogenic exposures with cumulative compound health impacts, including air pollution, noise exposure, artificial light at night, plastic pollution, chemical pollution and the various effects of climate change, such as heat extremes, desert storms, floods and wildfires. Urbanization has intensified the impact of many ERFs and created intense exposure environments, highlighting the urgency and the opportunity to address these for maximum public health benefit. Impactful intervention often requires regulatory and policy-driven efforts addressing the genesis of exposures and minimizes their health impact, particularly in vulnerable populations who may contribute the least but may be impacted the most. Solutions must involve the development of resiliency and adaptation measures to a changing world, where the probability of sudden catastrophic and cascading events is much more likely. Political will and international cooperation are essential in establishing and enforcing regulations that promote cleaner air and water, quieter and natural biodiverse environments, and sustainable infrastructure in urban, and rural medical facilities. Integration of planetary and environmental health into cardiovascular care will be vital in reducing the burden of NCDs globally. By addressing the root causes of environmental stressors, it is possible to reduce the incidence of CVDs and promote healthier, just and sustainable societies.

Journal of the American College of CardiologyVol. 87(11)
American Heart Association (US), Johannes Gutenberg University Mainz (DE), University of Lagos (NG), University Hospitals of Cleveland (US), University of Virginia Health System (US), European Society of Cardiology (FR), University Medical Center of the Johannes Gutenberg University Mainz (DE), Case Western Reserve University (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 85%
Climate Change and Health Impacts
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