Neutrophil‐Secreted Enzymes and <scp>ALS</scp> Risk: Exploring a Potential Mechanistic Link

Elevated neutrophil-secreted enzymes are associated with an increased risk of ALS occurrence. This finding provides mechanistic insight into neutrophil involvement in ALS and identifies these enzymes as potential therapeutic targets. ANN NEUROL 2026;99:591-605.

Authors

Institutions

Publication Details

Journal
Annals of Neurology
Published
2026-01-20
DOI
https://doi.org/10.1002/ana.78161
Citations
1
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
39.15
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Neutrophil‐Secreted Enzymes and ALS Risk: Exploring a Potential Mechanistic Link

Binbin Deng, Wen Cao, Ling Yu, Zhuoya Wang et al.
1 citations
Annals of Neurology
Amyotrophic Lateral Sclerosis Research
39.15
article

Neutrophil‐Secreted Enzymes and ALS Risk: Exploring a Potential Mechanistic Link

Binbin Deng, Wen Cao, Ling Yu, Zhuoya Wang, Dongsheng Fan
article en
1 citations

Abstract

Elevated neutrophil-secreted enzymes are associated with an increased risk of ALS occurrence. This finding provides mechanistic insight into neutrophil involvement in ALS and identifies these enzymes as potential therapeutic targets. ANN NEUROL 2026;99:591-605.

Annals of NeurologyVol. 99(3)
Peking University (CN), National Health and Family Planning Commission (CN), Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN), Biomarker Technologies (China) (CN), Ministry of Education (ME), Peking University Third Hospital (CN)
Openalex Percentile: Top 1%
Amyotrophic Lateral Sclerosis Research
39.15
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.