Undifferentiated pleomorphic sarcoma of bone (UPSB) treated in the German-speaking countries. A report of 132 unselected patients from the Cooperative Osteosarcoma Study Group (COSS)
UPSB generally affects considerably older persons than does the more frequent osteosarcoma. Despite a lower response rate to preoperative chemotherapy, its prognosis is at least comparable, if not better. Several prognostic factors impacting outcome could be defined. These results provide a benchmark for this rare disease.
Authors
- Semi Harrabi (ORCID: https://orcid.org/0000-0003-1195-7150)
- Thekla von Kalle (ORCID: https://orcid.org/0000-0001-8851-5014)
- Torsten Keßler (ORCID: https://orcid.org/0000-0001-7679-5362)
- Claudia Blattmann (ORCID: https://orcid.org/0000-0003-4045-5838)
- Peter Reichardt (ORCID: https://orcid.org/0009-0008-1410-3111)
- Benjamin Sorg
- Godehard Friedel (ORCID: https://orcid.org/0000-0002-0340-4719)
- Dimosthenis Andreou (ORCID: https://orcid.org/0000-0002-5083-9678)
- Matthias Kevric
- ANTONIA KNOLL
- Thomas Kühne
- Stefan S. Bielack
- Leo Kager
- Stefanie Hecker-Nolting
- Birgit Fröhlich
- Reinhard Windhager
- Daniel Baumhoer
Institutions
- University of Vienna (AT)
- University of Basel (CH)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Hospital of Basel (CH)
- Kantonsspital Baselland (CH)
- Universitätsklinikum Tübingen (DE)
- Klinik und Poliklinik für Psychosomatik und Psychotherapie (DE)
- Klinik und Poliklinik für Kinder- und Jugendmedizin (DE)
- Orthopädische Universitätsklinik (DE)
- Klinik und Poliklinik für Strahlentherapie und Radioonkologie (DE)
- Olgahospital (DE)
- St Anna Children's Hospital (AT)
- University Children’s Hospital Basel (CH)
- Klinik für Schlafmedizin (CH)
- Helios Hospital Berlin-Buch (DE)
- Klinikum Stuttgart (DE)
- St. Anna Children's Cancer Research Institute
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1007/s00432-025-06405-5
- Citations
- 2
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 72.89