Transfusion-related immunomodulation effect of erythrocyte characteristics on immune cells traits based on a multivariable Mendelian randomization study
Hemoglobin is the key erythrocyte characteristic underlying TRIM, which shows that increasing hemoglobin via blood transfusion increases the risk of TRIM. Hence, the benefits of blood transfusion that raise hemoglobin need to be weighed against the side effects.
Authors
- Baoji Hu (ORCID: https://orcid.org/0000-0001-6768-7984)
- Jinhuo Wang (ORCID: https://orcid.org/0009-0009-1493-7412)
- H. Wang
- Hao Li (ORCID: https://orcid.org/0000-0002-9886-1874)
- Zhanyu Cheng
- Jianrong Guo (ORCID: https://orcid.org/0009-0005-1064-025X)
- Lukun Wang
- Yue Ju
- Laiwei You
- Jie Wu
Institutions
- University of Shanghai for Science and Technology (CN)
- Second Military Medical University (CN)
- Pudong Medical Center (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1097/js9.0000000000004624
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00