Effect of SGLT-2 inhibitors on liver fibrosis progression in patients with MASLD: an updated meta-analysis based on RCTs

SGLT-2 inhibitors may delay the progression of liver fibrosis in patients with MASLD, particularly by improving serologic parameters. However, additional high-quality studies are needed to validate their clinical value.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-20
DOI
https://doi.org/10.3389/fmed.2025.1667823
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of SGLT-2 inhibitors on liver fibrosis progression in patients with MASLD: an updated meta-analysis based on RCTs

Anyi Xu, Jiale Ruan, Yingying Fang, Lei Yang
Frontiers in Medicine
Liver Disease Diagnosis and Treatment
article

Effect of SGLT-2 inhibitors on liver fibrosis progression in patients with MASLD: an updated meta-analysis based on RCTs

Anyi Xu, Jiale Ruan, Yingying Fang, Lei Yang
article en

Abstract

SGLT-2 inhibitors may delay the progression of liver fibrosis in patients with MASLD, particularly by improving serologic parameters. However, additional high-quality studies are needed to validate their clinical value.

Frontiers in MedicineVol. 12
Zhejiang Chinese Medical University (CN), Integrated Chinese Medicine (China) (HK)
Openalex Percentile: Top 84%
Liver Disease Diagnosis and Treatment
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