Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling
D-Exo is enriched with specific proteins, attenuates neuroinflammation and cognitive decline by regulating microglial M1/M2 polarization and AMPK pathway, highlighting its preventive potential.
Authors
- Jinhui Yang
- Haina Gao
- Wenya Jiao
- Wentao Qian (ORCID: https://orcid.org/0000-0002-4513-0218)
- Hongliang Li (ORCID: https://orcid.org/0000-0001-7094-2472)
- Wei Lü (ORCID: https://orcid.org/0000-0003-2600-6905)
- Jingru Zhao (ORCID: https://orcid.org/0000-0003-1184-2775)
- Yujie Li (ORCID: https://orcid.org/0009-0005-6783-3677)
- Menghui Wang
- Xinyuan Liao
- Yi Wang
- Pengjie Wang
Institutions
- Beijing Technology and Business University (CN)
- Beijing Biocytogen (China) (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Nutrients
- Published
- 2026-01-19
- DOI
- https://doi.org/10.3390/nu18020315
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Agricultural University
- Chinese Academy of Engineering