Long-term survival outcomes of laparoscopic total gastrectomy vs open total gastrectomy in patients with clinical stage I gastric cancer: the CLASS02 randomized clinical trial

Given the current underpowered long-term follow-up findings, LTG with D1 +/D2 lymphadenectomy performed by experienced surgeons showed numerically similar 5-year overall survival and disease-free survival rates to OTG in patients with clinical stage I gastric cancer.

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Publication Details

Journal
International Journal of Surgery
Published
2026-01-20
DOI
https://doi.org/10.1097/js9.0000000000004821
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Long-term survival outcomes of laparoscopic total gastrectomy vs open total gastrectomy in patients with clinical stage I gastric cancer: the CLASS02 randomized clinical trial

Y. Li, Jian Suo, Zekuan Xu, Aimin Li et al.
International Journal of Surgery
Gastric Cancer Management and Outcomes
article

Long-term survival outcomes of laparoscopic total gastrectomy vs open total gastrectomy in patients with clinical stage I gastric cancer: the CLASS02 randomized clinical trial

Y. Li, Jian Suo, Zekuan Xu, Aimin Li, Wei Zhang, Xuefei Wang, Kai Xu, Xiaohui Du, Zizhen Zhang, Naiqing Zhao, Yihong Sun, Peiwu Yu, Changming Huang, Jianxin Ye, Haojie Li, Peng Zhou, Hua Huang
article en

Abstract

Given the current underpowered long-term follow-up findings, LTG with D1 +/D2 lymphadenectomy performed by experienced surgeons showed numerically similar 5-year overall survival and disease-free survival rates to OTG in patients with clinical stage I gastric cancer.

International Journal of SurgeryVol. 112(3)
Fujian Medical University (CN), Sun Yat-sen University (CN), Jilin University (CN), Peking University (CN), Sichuan University (CN), Fudan University (CN), Guangdong General Hospital (CN), Renji Hospital (CN), Chinese PLA General Hospital (CN), West China Hospital of Sichuan University (CN), Fudan University Shanghai Cancer Center (CN), Peking University Cancer Hospital (CN), First Affiliated Hospital of Fujian Medical University (CN), Zhongshan Hospital of Xiamen University (CN), First Hospital of Jilin University (CN), Zhongshan Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Beijing Tsinghua Chang Gung Hospital (CN), Union Hospital (CN), Nanjing Medical University (CN), Chongqing Medical University (CN), Tsinghua University (CN)
Openalex Percentile: Top 85%
Gastric Cancer Management and Outcomes
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