Prognostic significance of PD-L1/PD-1 co-expression and CXCR3-driven inflammatory signatures in Egyptian patients with lymphoproliferative neoplasms

PD-L1/PD-1 co-expression with CXCR3, combined with SII and SIRI, constitutes a practical prognostic panel for staging and outcome prediction in Egyptian patients with LPNs. These biomarkers may guide personalized management and therapeutic monitoring.

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Publication Details

Journal
World Journal of Clinical Oncology
Published
2026-01-20
DOI
https://doi.org/10.5306/wjco.v17.i1.112801
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
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article

Prognostic significance of PD-L1/PD-1 co-expression and CXCR3-driven inflammatory signatures in Egyptian patients with lymphoproliferative neoplasms

Dalia Sherief, Emad Abd El Mongy Sadaka, Amira A A Othman, Aya Mohammed Abdelhameed et al.
World Journal of Clinical Oncology
Chronic Lymphocytic Leukemia Research
article

Prognostic significance of PD-L1/PD-1 co-expression and CXCR3-driven inflammatory signatures in Egyptian patients with lymphoproliferative neoplasms

Dalia Sherief, Emad Abd El Mongy Sadaka, Amira A A Othman, Aya Mohammed Abdelhameed, Rasha Elgamal, Nahla Nosair
article en

Abstract

PD-L1/PD-1 co-expression with CXCR3, combined with SII and SIRI, constitutes a practical prognostic panel for staging and outcome prediction in Egyptian patients with LPNs. These biomarkers may guide personalized management and therapeutic monitoring.

World Journal of Clinical OncologyVol. 17(1)
Suez University (EG), Kafrelsheikh University (EG)
Good health and well-being
Openalex Percentile: Top 84%
Chronic Lymphocytic Leukemia Research
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