Remove Oral Diphenhydramine From OTC—End the Status Quo

This Viewpoint describes adverse events associated with diphenhydramine and advocates for its withdrawal from over-the-counter (OTC) allergy medications.

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Publication Details

Journal
JAMA Internal Medicine
Published
2026-01-20
DOI
https://doi.org/10.1001/jamainternmed.2025.7278
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Remove Oral Diphenhydramine From OTC—End the Status Quo

Naclerio Rm, Meltzer Eo, Jaclyn Clark
JAMA Internal Medicine
Drug-Induced Adverse Reactions
article

Remove Oral Diphenhydramine From OTC—End the Status Quo

Naclerio Rm, Meltzer Eo, Jaclyn Clark
article en

Abstract

This Viewpoint describes adverse events associated with diphenhydramine and advocates for its withdrawal from over-the-counter (OTC) allergy medications.

JAMA Internal MedicineVol. 186(3)
La Jolla Institute for Immunology (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), University of California San Diego (US)
Openalex Percentile: Top 82%
Drug-Induced Adverse Reactions
DOISourceOpenAlex
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Remove Oral Diphenhydramine From OTC—End the Status Quo — Naclerio Rm, Meltzer Eo, et al. · JAMA Internal Medicine (2026) | TGRS Research Map | TGRS