Genomic analysis of a penicillin-susceptible, methicillin-resistant Staphylococcus aureus (ST9332) harboring triple mecA substitutions
CDSYY2023 is a PS-MRSA with triple-substituted mecA on a novel MLST background (ST9332). Its penicillin-susceptible/cefoxitin-resistant profile likely reflects a specific mecA sequence/regulatory context, highlighting the limits of relying solely on cefoxitin-based screening to infer β-lactam behaviour.
Authors
- Lin Lü (ORCID: https://orcid.org/0000-0002-2049-4605)
- Huarong Yu (ORCID: https://orcid.org/0000-0001-6996-915X)
- Yuting Sun (ORCID: https://orcid.org/0009-0009-5144-0931)
- Qiu Tang (ORCID: https://orcid.org/0000-0001-9424-3756)
- Fei Yan
- Jinxing Chen
Institutions
- University of Electronic Science and Technology of China (CN)
- Quzhou City People's Hospital (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1016/j.jgar.2026.01.004
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00