Impact of SNAP-25 MnlI polymorphism on brain activity patterns in children with ADHD: Insights from fractional amplitude of low-frequency fluctuation analysis

The SNAP-25 gene MnlI polymorphism has an impact on spontaneous brain activity in children with ADHD, as measured by fALFF. This study reveals the potential mechanisms from the perspective of brain networks, demonstrates how ADHD genotypes affect neural function, and provides a new approach for clinical decision-making and efficacy monitoring.

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Publication Details

Journal
Neuroimage Reports
Published
2026-01-20
DOI
https://doi.org/10.1016/j.ynirp.2026.100321
Primary Topic
Attention Deficit Hyperactivity Disorder
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of SNAP-25 MnlI polymorphism on brain activity patterns in children with ADHD: Insights from fractional amplitude of low-frequency fluctuation analysis

Xiaojing Lv, Hongwu Zeng, Guohua Liang, Wenxian Huang et al.
Neuroimage Reports
Attention Deficit Hyperactivity Disorder
article

Impact of SNAP-25 MnlI polymorphism on brain activity patterns in children with ADHD: Insights from fractional amplitude of low-frequency fluctuation analysis

Xiaojing Lv, Hongwu Zeng, Guohua Liang, Wenxian Huang, Binrang Yang, Tong Mo, Diangang Fang
article en

Abstract

The SNAP-25 gene MnlI polymorphism has an impact on spontaneous brain activity in children with ADHD, as measured by fALFF. This study reveals the potential mechanisms from the perspective of brain networks, demonstrates how ADHD genotypes affect neural function, and provides a new approach for clinical decision-making and efficacy monitoring.

Neuroimage ReportsVol. 6(1)
Shenzhen Children's Hospital (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 85%
Attention Deficit Hyperactivity Disorder
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