Ginseng acetylcholine from various ginsengs and its in vivo physiological effect

We determined acetylcholine (ACh) amount from live <i>Panax ginseng</i> (PG), <i>Panax quinquefolius</i> (PQ), and other ginsengs. We found that PG has more ACh content than that of PQ. PG-derived ACh fraction decreased <i>Daphnia pulex</i> heart rate, which was inhibited by atropine. PG-ACh-mediated regulations of heart rate involve muscarinic cholinergic pathway.

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Publication Details

Journal
Journal of Ginseng Research
Published
2026-01-19
DOI
https://doi.org/10.1016/j.jgr.2026.100979
Primary Topic
Ginseng Biological Effects and Applications
Type
article
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article

Ginseng acetylcholine from various ginsengs and its in vivo physiological effect

J. Y. Kim, Sung-Hee Hwang, Seung-Yeol Nah, Rami Lee
Journal of Ginseng Research
Ginseng Biological Effects and Applications
article

Ginseng acetylcholine from various ginsengs and its in vivo physiological effect

J. Y. Kim, Sung-Hee Hwang, Seung-Yeol Nah, Rami Lee
article en

Abstract

We determined acetylcholine (ACh) amount from live <i>Panax ginseng</i> (PG), <i>Panax quinquefolius</i> (PQ), and other ginsengs. We found that PG has more ACh content than that of PQ. PG-derived ACh fraction decreased <i>Daphnia pulex</i> heart rate, which was inhibited by atropine. PG-ACh-mediated regulations of heart rate involve muscarinic cholinergic pathway.

Journal of Ginseng ResearchVol. 50(2)
Konkuk University (KR), Rural Development Administration (KR), Sangji University (KR)
Good health and well-being
Openalex Percentile: Top 84%
Ginseng Biological Effects and Applications
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