Accuracy of frozen section for HPV-Associated squamous cell carcinoma of unknown primary
In this case series of 77 patients with SCCUP, the sensitivity and NPV of FSA for identification of the primary tumor was over 85%. FSA is valuable during diagnostic operation for SCCUP.
Authors
- S. Sridhar
- Mitra Mehrad (ORCID: https://orcid.org/0000-0003-4180-8180)
- Stacey Gargano (ORCID: https://orcid.org/0000-0002-2780-1866)
- Madalina Tuluc (ORCID: https://orcid.org/0000-0003-4920-3901)
- Annie E. Moroco (ORCID: https://orcid.org/0000-0002-8955-2826)
- Kyle Mannion (ORCID: https://orcid.org/0000-0001-9391-1791)
- Arielle G. Thal (ORCID: https://orcid.org/0000-0002-7498-8512)
- David M. Cognetti (ORCID: https://orcid.org/0000-0001-7039-3055)
- Melanie D. Hicks (ORCID: https://orcid.org/0000-0002-7162-3008)
- James S. Lewis
- Adam J. Luginbuhl
- Michael C. Topf
- Kim Ely
- Joseph M. Curry
- Shravan Gowrishankar
Institutions
- Thomas Jefferson University (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic Hospital (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Oral Oncology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1016/j.oraloncology.2026.107861
- Primary Topic
- Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00