Combination of brain injury and brain reserve promotes the neuroimaging evaluation of small vessel disease related cognitive impairment
Brain reserve protects cognitive function, potentially mediated in part through an optimized configuration of the brain structural network. The incorporation of conventional MRI biomarkers and brain structural network characteristics, encompassing both aspects of brain injury and reserve, holds promise for enhancing the clinical assessment of cognitive impairment related to CSVD.
Authors
- Yage Qiu (ORCID: https://orcid.org/0000-0002-5829-9434)
- Yuewei Chen
- Mianxin Liu
- Yan Zhou
- Yuanzheng Wang
- Ying Hu
- Qun Xu
- Yao Wang
- Xu Han
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Beijing Academy of Artificial Intelligence (CN)
- Shanghai Artificial Intelligence Laboratory (CN)
Publication Details
- Journal
- Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1016/j.pnpbp.2026.111615
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00