miR-194-5p-mediated suppression of protein tyrosine phosphatase non-receptor type 12 (PTPN12) expression in the thymus enhances immunologic functional restoration in aged mice
This study demonstrated that miR-194-5p modulates thymic immunological function in aged mice, highlighting its potential role in age-related thymic atrophy.
Authors
- Hui Huang (ORCID: https://orcid.org/0000-0002-4175-3979)
- Yong Zou
- Ka Chen
- Xia Shuai
- Ling-Yun Ai
- Zhi-Bin Guo
- Qing-Hua Hu
- Man-Qin Zhu
- Wei-Man Xu
Institutions
- Jiangxi Provincial Children's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1186/s40001-026-03865-4
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00