Vulvar Metastasis from Breast Cancer Treated with Abemaciclib plus Fulvestrant: A Case Report

This case underscores the importance of long-term follow-up of hormone-sensitive breast cancer, including thorough clinical examinations. To the best of our knowledge, this is the first reported case of vulvar metastasis from breast cancer that was successfully treated with the combination of abemaciclib and fulvestrant, leading to a complete response. The use of CDK4/6 inhibitors for the treatment of vulvar metastases of breast origin represents a significant advance, offering a less invasive and potentially more effective alternative to current treatment protocols.