Successful Bacteriophage Treatment of a Recalcitrant Intra-Abdominal Infection Caused by Multidrug-Resistant Pseudomonas aeruginosa in a 2-Year-Old Child
Antimicrobial resistance is life-threatening to pediatric patients with medical complexity who receive multiple courses of broad-spectrum antibiotics. Bacteriophages offer a safe treatment alternative when our antibiotic armamentarium is no longer sufficient. We describe successful use of bacteriophage therapy on a patient with a recalcitrant Pseudomonasaeruginosa infection after receiving a multiorgan transplant.
Authors
- Sanchi Malhotra (ORCID: https://orcid.org/0000-0002-2485-3927)
- Ishminder Kaur (ORCID: https://orcid.org/0000-0002-1759-8788)
- Keiko C. Salazar (ORCID: https://orcid.org/0000-0002-1845-281X)
- Suzanne V. McDiarmid
- Neema Pithia
- Robert S. Venick
- John S. Bradley
- Nanda Ramachandar
- Kristina Adachi
- Anthony Maresso
- Austin L. Terwilliger
Institutions
- Naval Medical Center San Diego (US)
- University of California, Los Angeles (US)
- Baylor College of Medicine (US)
- Rady Children's Hospital-San Diego (US)
Publication Details
- Journal
- The Journal of Pediatrics
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1016/j.jpeds.2026.115005
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 31.91
Funders
- U.S. Department of Defense
- U.S. Navy