Adaptive blood pressure–modulated atrial pacing in hypertensive HFpEF patients: a randomized, first-in-human study
In hypertensive patients with HFpEF and implanted pacemakers, BPAP safely improved exercise capacity and functional status compared to standard pacing. The approach demonstrates feasibility of home-based blood pressure-modulated pacing for physiologic rate adaptation. (NCT06036186).
Authors
- Eli S. Gang
- Michael Burnam
- SK Sinha
- Mukesh Jitendra Jha
- Sanjay Kumar Sharma (ORCID: https://orcid.org/0000-0002-5062-3199)
- Rohit Chopra
- Amitesh Nagarwal
Institutions
- Maharaja Engineering College (IN)
- NIMS University (IN)
- Ganesh Shankar Vidyarthi Memorial Medical College (IN)
- Art Research Centre of the Slovak Academy of Sciences (SK)
- Cedars-Sinai Smidt Heart Institute (US)
- DigitalSpace (United States) (US)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1093/eschf/xvaf020
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00