Kininogen-1 modulates cGMP-PKG signaling to alleviate inflammatory neuronal injury in intracerebral hemorrhage

Kng1 regulates the cGMP-PKG signaling pathway, influencing neuronal cell injury induced by the inflammatory response in ICH conditions. These findings suggest Kng1 as a potential therapeutic target for mitigating ICH-induced neuronal damage.

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Publication Details

Journal
Brain Research Bulletin
Published
2026-01-19
DOI
https://doi.org/10.1016/j.brainresbull.2026.111740
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
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article

Kininogen-1 modulates cGMP-PKG signaling to alleviate inflammatory neuronal injury in intracerebral hemorrhage

ShuWei Wang, Kaijie Wang, J. Li, Y Wang et al.
Brain Research Bulletin
Intracerebral and Subarachnoid Hemorrhage Research
article

Kininogen-1 modulates cGMP-PKG signaling to alleviate inflammatory neuronal injury in intracerebral hemorrhage

ShuWei Wang, Kaijie Wang, J. Li, Y Wang, Chaopeng Xu, Jing Zhao, Haoyu Wang
article en

Abstract

Kng1 regulates the cGMP-PKG signaling pathway, influencing neuronal cell injury induced by the inflammatory response in ICH conditions. These findings suggest Kng1 as a potential therapeutic target for mitigating ICH-induced neuronal damage.

Brain Research BulletinVol. 235
North China University of Science and Technology (CN), Tangshan Gongren Hospital (CN)
Good health and well-being
Openalex Percentile: Top 85%
Intracerebral and Subarachnoid Hemorrhage Research
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