Case Report: Personalized management of HER2-positive breast cancer with advanced nodal disease during pregnancy: a clinical case and review
This case underscores the value of personalized, multidisciplinary management in PrBC, particularly in patients with high-risk biologic features and advanced nodal disease. Integrating clinical judgment, genomic tools, and adaptive strategies, while accounting for gestational limitations, can optimize oncologic outcomes without compromising fetal safety.
Authors
- Sergi Ganau-Macías
- Isaac Cebrecos (ORCID: https://orcid.org/0000-0002-9333-3642)
- X. Bargalló
- Chiara Gullotta (ORCID: https://orcid.org/0000-0002-9201-8659)
- Gabriela Oses (ORCID: https://orcid.org/0000-0001-5843-0909)
- María José Senent Vidal
- E Seguí
- A. Prat
- B. Adamo
- Benjamin Walbaum
- Meritxell Molla
- Esther Sanfeliu
- Fara Braso-Maristany
- Eduard Mension
- Marta López
Institutions
- Pontificia Universidad Católica de Chile (CL)
- Breast Cancer Research Foundation (US)
- Departament de Salut (ES)
- Hospital Quirónsalud Barcelona (ES)
- Hospital Clínic de Barcelona (ES)
- Dana-Farber Cancer Institute (US)
- ID Genomics (United States) (US)
- Cancer Clinic (US)
- Campus Bio Medico University Hospital (IT)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.3389/fonc.2025.1672751
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00