Sex differences in thyroid dysfunction onset timing induced by immune checkpoint inhibitors: JADER disproportionality analysis

ICI-TD occurs earlier in female patients. This finding highlights the need for sex-specific monitoring to optimize early detection and management of thyroid-related adverse events in patients receiving ICIs.

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Publication Details

Journal
Expert Opinion on Drug Safety
Published
2026-01-19
DOI
https://doi.org/10.1080/14740338.2026.2618292
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Sex differences in thyroid dysfunction onset timing induced by immune checkpoint inhibitors: JADER disproportionality analysis

Ken-ichi Sako, Naohito Ide, Yuki Tsuruta, Tomoji Maeda
Expert Opinion on Drug Safety
Cancer Immunotherapy and Biomarkers
article

Sex differences in thyroid dysfunction onset timing induced by immune checkpoint inhibitors: JADER disproportionality analysis

Ken-ichi Sako, Naohito Ide, Yuki Tsuruta, Tomoji Maeda
article en

Abstract

ICI-TD occurs earlier in female patients. This finding highlights the need for sex-specific monitoring to optimize early detection and management of thyroid-related adverse events in patients receiving ICIs.

Expert Opinion on Drug Safety
Nihon Pharmaceutical University (JP)
Gender equality
Openalex Percentile: Top 84%
Cancer Immunotherapy and Biomarkers
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Sex differences in thyroid dysfunction onset timing induced by immune checkpoint inhibitors: JADER disproportionality analysis — Ken-ichi Sako, Naohito Ide, et al. · Expert Opinion on Drug Safety (2026) | TGRS Research Map | TGRS