Microvascular dysfunction in Takotsubo syndrome: a systematic review

MD in TTS has a variable prevalence. It is absent in a relevant proportion of the cases, making it questionable as it should be considered a pre-requisite for disease onset. The presence and extent of MD in TTS is a promising prognostic marker; no data in humans currently confirm its role as a therapeutic target.

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Publication Details

Journal
Postgraduate Medicine
Published
2026-01-02
DOI
https://doi.org/10.1080/00325481.2026.2616899
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
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article

Microvascular dysfunction in Takotsubo syndrome: a systematic review

Riccardo Improta, V Maestrini, Patrizia Spedicato, Gianluca Di Pietro et al.
Postgraduate Medicine
Takotsubo Cardiomyopathy and Associated Phenomena
article

Microvascular dysfunction in Takotsubo syndrome: a systematic review

Riccardo Improta, V Maestrini, Patrizia Spedicato, Gianluca Di Pietro, Lucrezia Netti, Luca Cacciotti, Giovanni Camastra, Luca Arcari, Salvatore Musarò, Beatrice Musumeci, Emanuele Barbato, Vittoria Cammisotto, Emanuela Belmonte, Francesco Marino, Pasquale Pignatelli
article en

Abstract

MD in TTS has a variable prevalence. It is absent in a relevant proportion of the cases, making it questionable as it should be considered a pre-requisite for disease onset. The presence and extent of MD in TTS is a promising prognostic marker; no data in humans currently confirm its role as a therapeutic target.

Postgraduate MedicineVol. 138(1)
Nini Hospital (LB), Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 85%
Takotsubo Cardiomyopathy and Associated Phenomena
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