Faecalibacterium prausnitzii Induces an Anti-inflammatory Response and a Metabolic Reprogramming in Human Monocytes
F prausnitzii induces an anti-inflammatory response and rewires energy metabolism in human monocytes in healthy and inflamed conditions, potentially explaining its beneficial impact on intestinal inflammation and human health in general. These results provide new insight into the mechanisms underlying the anti-inflammatory effects of F prausnitzii and are crucial for a better understanding of its potential use in IBD treatment.
Authors
- Laura Creusot (ORCID: https://orcid.org/0000-0002-3882-8423)
- Hang‐Phuong Pham (ORCID: https://orcid.org/0000-0002-7896-7401)
- Rodrigo de Oliveira Formiga (ORCID: https://orcid.org/0000-0001-5475-0067)
- Camille Danne (ORCID: https://orcid.org/0000-0003-0971-8310)
- Iria Alonso Salgueiro
- Marie‐Laure Michel (ORCID: https://orcid.org/0000-0003-2657-4662)
- Pauline Ruffié
- Nathalie Rolhion (ORCID: https://orcid.org/0000-0002-2946-4808)
- Laura Hua
- Florian Marquet
- Loïc Brot
- Delphine Sedda
- Harry Sokol
- Philippe Langella
- Jérémie H. Lefevre
Institutions
- Université Paris-Saclay (FR)
- Microbiologie de l’alimentation au service de la santé (FR)
- Sorbonne Université (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Hôpital Saint-Antoine (FR)
- Fédération Hospitalo-Universitaire, Paris Center for Microbiome Medicine (FR)
- Centre de Recherche Saint-Antoine (FR)
Publication Details
- Journal
- Gastroenterology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1053/j.gastro.2025.10.003
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 22.24