Penetration enhancement effects of topically applied crosslinked hyaluronic acid
Crosslinked HA can boost the topical delivery of relevant skincare actives that range in size from small-molecule actives (<500 Da) to large macromolecules (>10 000 Da) like linear HA itself. Combined with its well-established and previously documented skin benefits, this makes crosslinked HA a highly versatile ingredient for topical skincare products.
Authors
- Krystal L. House (ORCID: https://orcid.org/0000-0002-8297-2756)
- Aaron Cohen
- David Bonnel (ORCID: https://orcid.org/0009-0004-4159-261X)
- Raphaël Legouffe (ORCID: https://orcid.org/0000-0002-2421-1385)
- Aurore Tomezyk
- Paul Duhamel
- M. Gaudin
- Junhong Mao
Institutions
- Alimentation et Sciences Sociales (FR)
- Colgate-Palmolive (United States) (US)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1111/ics.70076
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00