Prolonged progression-free survival with zanubrutinib in relapsed/refractory CLL: an indirect treatment comparison versus other BTK inhibitors using multilevel network meta-regression

This ML-NMR suggests that zanubrutinib offers improved PFS compared to ibrutinib and acalabrutinib in both general and high-risk R/R CLL populations. OS results were uncertain due to limited follow-up.

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Publication Details

Journal
Journal of Medical Economics
Published
2026-01-19
DOI
https://doi.org/10.1080/13696998.2025.2609514
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

Prolonged progression-free survival with zanubrutinib in relapsed/refractory CLL: an indirect treatment comparison versus other BTK inhibitors using multilevel network meta-regression

Walter Bouwmeester, Leyla Mohseninejad, Keri Yang, Milica Jevdjevic et al.
Journal of Medical Economics
Chronic Lymphocytic Leukemia Research
article

Prolonged progression-free survival with zanubrutinib in relapsed/refractory CLL: an indirect treatment comparison versus other BTK inhibitors using multilevel network meta-regression

Walter Bouwmeester, Leyla Mohseninejad, Keri Yang, Milica Jevdjevic, Jeroen P Jansen, Mazyar Shadman, Rhys Williams, Sheng Xu
article en

Abstract

This ML-NMR suggests that zanubrutinib offers improved PFS compared to ibrutinib and acalabrutinib in both general and high-risk R/R CLL populations. OS results were uncertain due to limited follow-up.

Journal of Medical EconomicsVol. 29(1)
National University of Misiones (AR), Fred Hutch Cancer Center (US), Precision Research (United States) (US)
Zero hunger
Openalex Percentile: Top 85%
Chronic Lymphocytic Leukemia Research
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