Importance of basic science and research training for the future generation of cardiologists

Advances in the battle against cardiovascular diseases depend upon continuously translating emerging scientific knowledge from preclinical studies and clinical trials into innovative and effective therapeutic strategies. Over the past three decades, molecular and cellular biology have undergone a profound transformation, and large-scale, single-cell, and multi-omics studies have enabled investigations on cardiac disease mechanisms with unprecedented precision. However, these rapid advancements have also contributed to a divergence between the needs and aspirations of basic researchers and those of clinical scientists and practicians, to the detriment of discovery science, precision medicine, and cardiovascular healthcare. The present document highlights the importance of education and training in overcoming the gap between discovery and clinical science, by promoting a common language aimed at designing more translationally relevant and impactful discovery science. To achieve this aim, multidisciplinary efforts will be required to better define learning objectives within training programmes, including education in discovery and clinical sciences, promotion of specific mentorship paths, collaborative research efforts, promotion of equality, diversity, and inclusion, and protection of research time and activity within academic, clinical, and research careers.

Authors

Publication Details

Journal
Universität Zürich, ZORA
Published
2025-09-25
DOI
https://doi.org/10.5167/uzh-281987
Primary Topic
Cardiac Fibrosis and Remodeling
Type
article
Field-Weighted Citation Impact
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article

Importance of basic science and research training for the future generation of cardiologists

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Universität Zürich, ZORA
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Importance of basic science and research training for the future generation of cardiologists

Ioanna Andreadou, Ange Maguy, Mélanie Paillard, Petra Kleinbongard, Sean M Davidson, Zoltan Giricz, Julien Barc, Johann Wojta, Radoslaw Parma, Cecilia Linde, Maurizio Pesce, Elisa Liehn, Matthias Thielmann, Bianca J J M Brundel, María Rubini Giménez, et al., Carlo G Tocchetti, Katrin Streckfuss-Bömeke, Theresa McDonagh, Sophie Van Linthout, Thomas F Lüscher, Panagiotis Vardas, Paul C Evans, Perry M Elliott, Gemma Chiva-Blanch, Can Gollmann-Tepeköylü, Tomasz Guzik, Pascal Vranckx, Thomas Krieg, Giulio Pompilio, Monika Gladka
article en

Abstract

Advances in the battle against cardiovascular diseases depend upon continuously translating emerging scientific knowledge from preclinical studies and clinical trials into innovative and effective therapeutic strategies. Over the past three decades, molecular and cellular biology have undergone a profound transformation, and large-scale, single-cell, and multi-omics studies have enabled investigations on cardiac disease mechanisms with unprecedented precision. However, these rapid advancements have also contributed to a divergence between the needs and aspirations of basic researchers and those of clinical scientists and practicians, to the detriment of discovery science, precision medicine, and cardiovascular healthcare. The present document highlights the importance of education and training in overcoming the gap between discovery and clinical science, by promoting a common language aimed at designing more translationally relevant and impactful discovery science. To achieve this aim, multidisciplinary efforts will be required to better define learning objectives within training programmes, including education in discovery and clinical sciences, promotion of specific mentorship paths, collaborative research efforts, promotion of equality, diversity, and inclusion, and protection of research time and activity within academic, clinical, and research careers.

Universität Zürich, ZORA
Reduced inequalities
Openalex Percentile: Top 29%
Cardiac Fibrosis and Remodeling
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